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Takahashi S. And scientists in Oregon managed to clone a human embryonic stem cell line by nuclear transfer Air Jordan Black

´╗┐dential hopefuls one of whom could be elected in 2016 support reinstating the Bush era restrictions Nike Jordan Gold

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or even an outright ban on funding the work. Klein points out that 26 states are led by legislatures that oppose the research. Moreover, funding for the National Institutes of Health (NIH) has taken a hit and the agency closed its Center for Regenerative Medicine in April (see Nature 508, 157; 2014). This is the case that Klein plans to lay before the voters. Nike Air Jordan 11 Low

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(M. Tachibana et al. Some treatments are progressing faster outside California, too. Japan, for instance, has raced ahead of the rest of the world in testing iPS cells as therapies for conditions such age related macular degeneration, which can cause blindness (see Nature 494, 413; 2013). But in California, researchers are making nerve, heart, eye and skin cells from iPS cells and embryonic stem cells a range of work rare for a single state and they aim to test many of these in humans. They are developing drugs against cancer stem cells, which are thought to perpetuate the disease. And they are leading the world's only two trials of treatments that combine gene editing and cell therapy to treat HIV.

They are doing all this with an unmatched infrastructure, including a network of 12 new or newly renovated facilities, and a funding pipeline that acts as a beacon to young scientists. "Almost every country would be jealous of what they've got in California," says Christine Mummery of the Leiden University Medical Center in the Netherlands. Top flight scientists such as Clive Svendsen, formerly at the University of Wisconsin Madison, have flocked to the state, she says. But, she adds, "they haven't cured a patient, which is the critique". That critique frequently bubbles to the surface. On 22 January, Thomas and CIRM's senior vice president of research and development, Ellen Feigal, faced uncomfortable questions from the state's Citizens Financial Accountability and Oversight Committee at a meeting in Los Angeles. Committee member Jim Lott a health care executive and father of a 13 year old daughter with a spinal cord injury grew frustrated as he listened to the pair run through PowerPoint slides full of numbers and abstract language touting the agency's scientific accomplishments. None of the slides told him what CIRM had done that would get his daughter out of her wheelchair.

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"We have to protect science's access to the full range of cellular types now," he says. "And in doing that, we will protect the freedom of science to ethically pursue knowledge in this country outside of religious ideology. "His focus on a 'full range' of cells reflects the ways Air Jordan Boots in which the stem cell field has blossomed in the past decade, changing in ways that no one expected when Klein first proposed CIRM. And the biggest breakthroughs have come from outside California. A Japanese group, for example, discovered how to create induced pluripotent stem (iPS) cells (K.

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